Desktop Small-Scale Esterification Unit

The benchtop small-scale esterification unit is equipped with a 250 mL reaction vessel, allowing precise control of the vacuum level within the reactor and enabling efficient removal of water and alcohol. The collection tank is transparent and is followed by a molecular sieve and a vacuum pump. This equipment is ideal for evaluating conversion efficiency by adjusting the vacuum level, with a controllable vacuum range of 0.04–0.095 MPa, making it well suited for both production and research applications. Combined with scale-up studies, it is the preferred choice for small-scale esterification in universities and research institutions.

Classification:

Polymerization Reactor

Messageboard

Telephone:

400-920-1718

Product Description

Core Features

Precision Vacuum Control
- Wide adjustment range (0.04–0.095 MPa): By precisely controlling the vacuum level, water/alcohol generated during the reaction can be dynamically removed, shifting the esterification equilibrium toward the product side and significantly enhancing the conversion rate.
- Online Monitoring Feedback Optional vacuum sensors and automated control systems are available to record and adjust pressure in real time, ensuring reproducibility of reactions.
Modular and Highly Efficient Separation
- Visual Collection Canister The transparent design allows real‑time observation of the distillate’s condition (such as phase separation), making it easy to quickly assess the reaction progress.
- Molecular Sieve–Vacuum Pump Combination Molecular sieves adsorb residual moisture and alcohols, protecting the vacuum pump and enhancing recovery purity, making them suitable for systems that are sensitive to byproducts (such as pharmaceutical intermediates).
Pilot-to-Production Scale-Up Design
- 250 mL Standard Reactor : Compatible with common small-scale trials, the data can be directly used to extrapolate parameters for pilot-scale scaling (such as vacuum gradients and temperature–pressure coupling effects).
- Multi‑interface scalability : Provide reserved feed ports, temperature measurement ports, and sampling valves to support continuous feeding or online analysis (such as FTIR monitoring of functional group changes).
Security and User-Friendliness
- Explosion‑proof and corrosion‑resistant material The reactor vessel is made of borosilicate glass or Hastelloy, resistant to acidic catalysts (such as concentrated sulfuric acid and p‑toluenesulfonic acid) and high temperatures (up to 200°C).
- Compact desktop layout Saves laboratory space, and the one‑click operation interface lowers the barrier to entry.

Application Scenario Expansion

Scientific Research and Innovation
- Mechanism Research By varying the vacuum level, we can investigate reaction kinetics and optimize esterification conditions, such as enhancing the efficiency of water removal via vacuum azeotropic distillation.
- Verification of New Catalysts Quickly compare the differences in activity of various catalysts (enzymes, ionic liquids, etc.) under low-pressure conditions.
Process Development
- Synthesis of High-Boiling Esters For example, phthalates can be processed by gradually reducing pressure to prevent the thermal degradation of sensitive products.
- Azeotropic System Treatment : Products that form azeotropes with water/alcohol (such as for the purification of ethyl acetate).
Education and Training
- Teaching Demonstration : Clearly demonstrates the application of Le Chatelier’s Principle in esterification reactions, suitable for chemical engineering laboratory courses.
Industry Adaptation
- Fine Chemicals : Small-batch trial production of spices (isoamyl acetate), plasticizers, and other materials.
- Biofuel Screening of process parameters for fatty acid methyl esters (biodiesel).

Details

Technical parameters

Product Description
Technical parameters
Product Details Chart

Details
Core Features
1. Precision Vacuum Control
  - Wide adjustment range (0.04–0.095 MPa): By precisely controlling the vacuum level, water/alcohol generated during the reaction can be dynamically removed, shifting the esterification equilibrium toward the product side and significantly enhancing the conversion rate.
  - Online Monitoring Feedback Optional vacuum sensors and automated control systems are available to record and adjust pressure in real time, ensuring reproducibility of reactions.
2. Modular and Highly Efficient Separation
  - Visual Collection Canister The transparent design allows real‑time observation of the distillate’s condition (such as phase separation), making it easy to quickly assess the reaction progress.
  - Molecular Sieve–Vacuum Pump Combination Molecular sieves adsorb residual moisture and alcohols, protecting the vacuum pump and enhancing recovery purity, making them suitable for systems that are sensitive to byproducts (such as pharmaceutical intermediates).
3. Pilot-to-Production Scale-Up Design
  - 250 mL Standard Reactor : Compatible with common small-scale trials, the data can be directly used to extrapolate parameters for pilot-scale scaling (such as vacuum gradients and temperature–pressure coupling effects).
  - Multi‑interface scalability : Provide reserved feed ports, temperature measurement ports, and sampling valves to support continuous feeding or online analysis (such as FTIR monitoring of functional group changes).
4. Security and User-Friendliness
  - Explosion‑proof and corrosion‑resistant material The reactor vessel is made of borosilicate glass or Hastelloy, resistant to acidic catalysts (such as concentrated sulfuric acid and p‑toluenesulfonic acid) and high temperatures (up to 200°C).
  - Compact desktop layout Saves laboratory space, and the one‑click operation interface lowers the barrier to entry.
Application Scenario Expansion
1. Scientific Research and Innovation
  - Mechanism Research By varying the vacuum level, we can investigate reaction kinetics and optimize esterification conditions, such as enhancing the efficiency of water removal via vacuum azeotropic distillation.
  - Verification of New Catalysts Quickly compare the differences in activity of various catalysts (enzymes, ionic liquids, etc.) under low-pressure conditions.
2. Process Development
  - Synthesis of High-Boiling Esters For example, phthalates can be processed by gradually reducing pressure to prevent the thermal degradation of sensitive products.
  - Azeotropic System Treatment : Products that form azeotropes with water/alcohol (such as for the purification of ethyl acetate).
3. Education and Training
  - Teaching Demonstration : Clearly demonstrates the application of Le Chatelier’s Principle in esterification reactions, suitable for chemical engineering laboratory courses.
4. Industry Adaptation
  - Fine Chemicals : Small-batch trial production of spices (isoamyl acetate), plasticizers, and other materials.
  - Biofuel Screening of process parameters for fatty acid methyl esters (biodiesel).

Product Description
Technical parameters
Product Details Chart

Core Features
1. Precision Vacuum Control
  - Wide adjustment range (0.04–0.095 MPa): By precisely controlling the vacuum level, water/alcohol generated during the reaction can be dynamically removed, shifting the esterification equilibrium toward the product side and significantly enhancing the conversion rate.
  - Online Monitoring Feedback Optional vacuum sensors and automated control systems are available to record and adjust pressure in real time, ensuring reproducibility of reactions.
2. Modular and Highly Efficient Separation
  - Visual Collection Canister The transparent design allows real‑time observation of the distillate’s condition (such as phase separation), making it easy to quickly assess the reaction progress.
  - Molecular Sieve–Vacuum Pump Combination Molecular sieves adsorb residual moisture and alcohols, protecting the vacuum pump and enhancing recovery purity, making them suitable for systems that are sensitive to byproducts (such as pharmaceutical intermediates).
3. Pilot-to-Production Scale-Up Design
  - 250 mL Standard Reactor : Compatible with common small-scale trials, the data can be directly used to extrapolate parameters for pilot-scale scaling (such as vacuum gradients and temperature–pressure coupling effects).
  - Multi‑interface scalability : Provide reserved feed ports, temperature measurement ports, and sampling valves to support continuous feeding or online analysis (such as FTIR monitoring of functional group changes).
4. Security and User-Friendliness
  - Explosion‑proof and corrosion‑resistant material The reactor vessel is made of borosilicate glass or Hastelloy, resistant to acidic catalysts (such as concentrated sulfuric acid and p‑toluenesulfonic acid) and high temperatures (up to 200°C).
  - Compact desktop layout Saves laboratory space, and the one‑click operation interface lowers the barrier to entry.
Application Scenario Expansion
1. Scientific Research and Innovation
  - Mechanism Research By varying the vacuum level, we can investigate reaction kinetics and optimize esterification conditions, such as enhancing the efficiency of water removal via vacuum azeotropic distillation.
  - Verification of New Catalysts Quickly compare the differences in activity of various catalysts (enzymes, ionic liquids, etc.) under low-pressure conditions.
2. Process Development
  - Synthesis of High-Boiling Esters For example, phthalates can be processed by gradually reducing pressure to prevent the thermal degradation of sensitive products.
  - Azeotropic System Treatment : Products that form azeotropes with water/alcohol (such as for the purification of ethyl acetate).
3. Education and Training
  - Teaching Demonstration : Clearly demonstrates the application of Le Chatelier’s Principle in esterification reactions, suitable for chemical engineering laboratory courses.
4. Industry Adaptation
  - Fine Chemicals : Small-batch trial production of spices (isoamyl acetate), plasticizers, and other materials.
  - Biofuel Screening of process parameters for fatty acid methyl esters (biodiesel).
技术参数
技术参数